
Mission District Holidays
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Your Mission District Holiday
Experience all the wonderful things this neighbourhood has to offer with a tailor-made Mission District holiday package. However you picture yourself spending your days here, you'll find countless opportunities for fun, relaxation and adventure. Can't wait to get out and see the sights during your trip to Mission District? Be sure to check out nearby attractions like Lombard Street, University of San Francisco and University of California, San Francisco. Expedia is here to put your plans into action. Book your perfect Mission District holiday now.
Our guide on where to stay in Mission District

Fisherman's Wharf
This waterfront location is steeped in history dating back to the days of the gold rush. Today, visitors come here for its vibrant atmosphere and great food.

Union Square
Packed with a treasure trove of upmarket boutiques, designer labels and department store, shoppers will love this huge shopping plaza.

Downtown San Francisco
Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market
South of Market, or “SoMa” to the “SoCal” locals, is a huge, varied and exciting district in downtown “San Fran”.

Nob Hill
If you guessed that Nob Hill was one of San Francisco’s original “Seven Hills,” then you might just be a genius.
Our pick of the best Mission District Hotel Deals

Holiday Inn Golden Gateway by IHG

Hotel Riu Plaza Fisherman's Wharf
"Clean room; breakfast was great and we got to check in a couple hours early!!"
Reviewed on 18 Aug 2026

Handlery Union Square Hotel
"Lovely hotel. Staff very helpful. We didn’t use the pool as too busy sightseeing but was told it was heated and open 8am to 8pm. Room was clean and had a good size bed with tv. Shower and bathroom was adequate for what I needed. Would stay here again if in San Francisco."
Reviewed on 18 Aug 2026
Frequently asked questions
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Stay near popular Mission District attractions

Mission Dolores Park
Mission San Francisco de Asís

Balmy Alley
Southern Exposure
San Francisco Public Library
SF Armory
Brick & Mortar Music Hall
The Great Northern
Activities

Golden Gate Bay Cruise - Sail Around Alcatraz! (1-hour)

Go City: San Francisco All-Inclusive Pass with 30+ Attractions











